At this moment, EPlusTV is far less resource intensive and machine intrusive than PrismCast, and much more intuitive to set up. Not knocking PrismCast, I love what it does, but I'm staring at a permanent Chrome session on my task bar right now because I had to install the NPM version to get acceptable performance in Windows; the Docker just didn't cut it. This is as opposed to EPlusTV, which is just serving up streams from the Docker for pretty much no overhead. I almost never have to think about what EPlusTV is doing, whereas PrismCast needs a bit of babysitting.
With time, though, a lot of that may change. PrismCast has a ton of development going on and is getting better all the time, so many of these small issues may disappear! Perhaps it will even incorporate the way EPlusTV does logging in to providers (or something like it), and maintain native streams without having to do as many page-loading steps, thus making things more efficient. I guess what I'm trying to say is that at this particular juncture, EPlusTV has some advantages, but that may not be true in the future.