Some thoughts since I've used the LinkPi devices for quite a while during ADBTuner development.
Like most of these encoders, the LinkPi devices are a security nightmare. I stumbled across this documentation that is helpful in identifying these security concerns and correcting them. If you have the opportunity to, isolate these devices on your network. GitHub - matiaspl/LinkPi-ENCx
Disable streams you are not going to use to reduce CPU load.
Leaving only one enabled in the "Encode" section here is recommended.
For ADBTuner usage, turn off all protocols in the "Stream" section except HTTP
Encoder settings. Since it's running on the internal network I prefer to run a relatively high bitrate to minimize compression artifacts.
2025 Edit: Some LinkPi devices (seemingly newer ones than the ENC1V2) do not do well in AVBR mode. The bitrate drops too low during scene transitions which causes a ton of macroblocking. Based on this experience I would now recommend VBR mode instead.
LinkPi recommends average bitrate (AVBR) encoding so I went with that and an average bitrate of 8500. Everyone should bump the framerate to 60fps and a 2 second GOP setting is reasonable. Disable any sub-streams (set codec to "close").
H.264 is highly recommended. It's easier to decode and at least for ADBTuner it works more reliably (h265 sometimes doesn't decode correctly when trying to automatically perform OCR to click "ok" buttons and such)